BDBM50104694 (R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2(5H)-one::(R)-5-Ethyl-3-hexadecanoyl-4-methyl-5H-furan-2-oneo::3-Hexadecanoyl-4-hydroxy-5-hydroxymethyl-5H-furan-2-one::CHEMBL108441::RK-682

SMILES CCCCCCCCCCCCCCCC(=O)c1c(O)oc(CO)c1O

InChI Key InChIKey=BKBKOAWPAIKUCJ-UHFFFAOYSA-N

Data  27 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50104694   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human recombinant PTP1B assessed as p-nitorphenol production after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.49E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  700nMAssay Description:Inhibition of 6-His-N-terminal tagged human PTP1B expressed in Escherichia coli BL21 (DE3) cells assessed as pNP formation using pNPP as substrate in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+4nMAssay Description:Inhibition of PTP1B by colorimetric assayChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using p-nitrophenyl phosphate as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  5.62E+3nMAssay Description:Inhibition of PTP1B (unknown origin) assessed as decrease in p-nitrophenol production from pNPP substrate after 30 mins by HTS7000 bioassay reader an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant PTP1B assessed as p-nitrophenol productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibition of human recombinant PTP1B after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Toho University

Curated by ChEMBL
LigandPNGBDBM50104694((R)-4-hydroxy-5-(hydroxymethyl)-3-palmitoylfuran-2...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human recombinant PTP1B using p-nitrophenyl phosphate as substrate assessed as p-nitrophenol release after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed